Company Filing History:
Years Active: 1998
Title: The Innovations of Charles I Cooney
Introduction
Charles I Cooney is a notable inventor based in Brookline, MA (US). He has made significant contributions to the field of biotechnology, particularly in the area of genetic engineering. His work has implications for medical research and therapeutic applications.
Latest Patents
One of Cooney's key patents is titled "Method for obtaining a modified heparinase gene." This patent describes the cloning of the heparinase gene from Flavobacterium Heparinum using the polymerase chain reaction. The Open Reading Frame (ORF) corresponds to 1152 base pairs, encoding a precursor protein with a molecular weight of 43,800 daltons. The amino acid sequence reveals a 20-residue leader peptide, and the gene was expressed in two expression systems in E. coli. This innovation showcases Cooney's expertise in molecular biology and genetic manipulation.
Career Highlights
Cooney is affiliated with the Massachusetts Institute of Technology, where he has contributed to various research projects and initiatives. His work has been instrumental in advancing the understanding of heparinase and its potential applications in medicine.
Collaborations
Cooney has collaborated with notable researchers such as Ramnath Sasisekharan and Kelley Wilson Moremen. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Charles I Cooney's contributions to biotechnology and genetic engineering are noteworthy. His innovative patent on the heparinase gene exemplifies his commitment to advancing scientific knowledge and improving medical therapies.