Chang Xu

Title: Chang Xu: Innovator in Immunomodulatory Hydrogels

Introduction

Chang Xu is a prominent inventor based in Tianjin, China. He has made significant contributions to the field of biomedical engineering, particularly in the development of immunomodulatory hydrogels. His innovative work has the potential to impact various medical applications.

Latest Patents

Chang Xu holds a patent for an "Immunomodulatory hydrogel and preparation method thereof." This patent describes a method for preparing an immunomodulatory hydrogel using methoxy polyethylene glycol amine (mPEG-NH) as an initiator. The mPEG-NH reacts with L-tyrosine-N-carboxyanhydrides (L-Tyr-NCAs) to form a methoxy polyethylene glycol-poly L-tyrosine (PETyr) block copolymer. The PETyr is then reacted with tyrosinase to create an oxidized methoxy polyethylene glycol-poly L-tyrosine copolymer (PETO). By co-dissolving the PETO with octyl itaconate nanomicelles (ITA8) in a disperse medium, an itaconic acid-loaded immunomodulatory hydrogel (PETO-ITA8) is obtained. This innovative approach showcases his expertise in polymer chemistry and its applications in medicine.

Career Highlights

Chang Xu is affiliated with the Institute of Radiation Medicine, Chinese Academy of Medical Sciences, and Peking Union Medical College. His work at these prestigious institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Chang Xu has worked alongside notable colleagues, including Huijuan Song and Qiang Liu. Their collaborative efforts have further advanced the research and development of innovative medical solutions.

Conclusion

Chang Xu's contributions to the field of immunomodulatory hydrogels exemplify his dedication to advancing medical technology. His innovative patent and collaborative work position him as a key figure in biomedical research.