Seoul, South Korea

Chang Ju Choi


 

Average Co-Inventor Count = 8.0

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2012

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1 patent (USPTO):Explore Patents

Title: Innovator Chang Ju Choi: A Pioneer in Pharmaceutical Chemistry

Introduction

Chang Ju Choi, based in Seoul, South Korea, is an accomplished inventor recognized for his contributions to the field of pharmaceutical chemistry. He holds one significant patent that has made a mark in the production of voriconazole, a vital antifungal medication widely used in treating various infections.

Latest Patents

Choi's patent, titled "Process for preparing voriconazole," presents a novel method for synthesizing optically pure voriconazole with high yield. The process includes several steps: first, it involves subjecting 1-(2,4-difluorophenyl)-2(1H-1,2,4-triazol-1-yl)ethanone to a Reformatsky-type coupling reaction with a substituted thiopyrimidine derivative to obtain a desired enantiomeric pair. Subsequently, the thiol derivative is removed from the enantiomer, leading to the production of racemic voriconazole. Finally, the racemic voriconazole is isolated through optical resolution using an optically active acid.

Career Highlights

Choi’s affiliation with Hanmi Science reflects his commitment to advancing pharmaceutical research and development. His innovative approach to drug synthesis not only enhances the efficiency of producing critical medications but also aligns with contemporary trends in pharmaceutical sciences. His contributions have been pivotal in improving the availability and purity of therapeutic options for patients.

Collaborations

Within Hanmi Science, Chang Ju Choi collaborates with notable colleagues such as Young Ho Moon and Moon Sub Lee. Together, they foster a creative and innovative environment that encourages groundbreaking research and development in the pharmaceutical sector.

Conclusion

Chang Ju Choi stands as a testament to the impact of innovation in pharmaceutical chemistry. His patent on voriconazole preparation exemplifies his expertise and dedication to improving medical treatments. As the industry evolves, Choi’s contributions are sure to play a crucial role in shaping the future of drug discovery and development.

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