Company Filing History:
Years Active: 1994-2002
Title: The Innovative Contributions of Catherine D. Strader
Introduction
Catherine D. Strader is a prominent inventor based in Verona, NJ (US), known for her significant contributions to the field of biochemistry and pharmacology. With a total of 12 patents to her name, she has made remarkable advancements in understanding and manipulating human receptors, which are crucial for developing new therapeutic drugs.
Latest Patents
One of her latest patents is titled "Cloned and expressed human bradykinin BK-2 receptor." This invention involves a cloned human BK-2 bradykinin receptor derived from a human lung fibroblast cell line. The cDNA clone encodes a novel 364 amino acid protein that exhibits the characteristics of a seven transmembrane domain G-protein coupled receptor. This invention is instrumental in expressing a BK-2 bradykinin receptor in host mammalian cells, facilitating the screening for pharmaceutical antagonists or agonists that interact with the BK-2 bradykinin receptor protein. Another significant patent is the "Method for measuring human neurokinin-3 receptor ligand binding." This patent discloses a recombinant human neurokinin-3 receptor, prepared using polymerase chain reaction techniques. It includes the complete sequence of human NK3R complementary DNA and describes expression systems, such as a CHO (Chinese hamster ovarian cell line) stable expression system. The human NK3R can be utilized in assays to identify and evaluate entities that bind to the neurokinin-3 receptor.
Career Highlights
Catherine has had a distinguished career, working with notable organizations such as Merck & Company, Inc. and the University of Pennsylvania. Her work in these institutions has allowed her to collaborate with leading scientists and contribute to groundbreaking research in receptor biology.
Collaborations
Throughout her career, Catherine has collaborated with esteemed colleagues, including Tung M. Fong and Margaret A. Cascieri. These partnerships have further enhanced her research and innovation in the field.
Conclusion
Catherine D. Strader's innovative work and numerous patents have significantly impacted the understanding of human receptors and their applications in drug development. Her contributions continue to inspire future research in pharmacology and biochemistry.
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