Company Filing History:
Years Active: 1977-1982
Title: Candice B Biggs: Innovator in Microbial Steroid Degradation
Introduction
Candice B Biggs is a notable inventor based in Kalamazoo, MI, recognized for her contributions to the field of microbiology and biotechnology. With a remarkable portfolio of nine patents, her work focuses on developing innovative processes to utilize microorganism mutants for the conversion of sterols into valuable steroid intermediates.
Latest Patents
Among her latest patents, Candice has created mutants of Mycobacterium phlei that selectively degrade steroids with 17-alkyl side chains ranging from 2 to 10 carbon atoms. This process predominantly yields androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione (AD). These metabolites serve as essential intermediates for the synthesis of useful steroids, highlighting the significance of her research in pharmaceutical applications.
Another notable patent involves the microorganism mutant that facilitates the conversion of sterols into androsta-4-ene-3,17-dione, achieving a similar degradation process with a focus on producing predominantly AD and trace amounts of ADD. The methods developed from these patents showcase innovations that significantly advance the capabilities in steroid degradation.
Career Highlights
Candice B Biggs serves as an influential figure in The Upjohn Company, where her research has gained considerable attention in the scientific community. Her expertise in microbiological processes has not only contributed to the advancement of biotechnology but has also opened new opportunities for practical applications in the industry.
Collaborations
Throughout her career, Candice has collaborated with esteemed coworkers such as Merle G Wovcha and Thomas R Pyke. These partnerships have enabled cross-functional discussions and research efforts, leading to the successful development of innovative solutions in the realm of microbial processes and steroid degradation.
Conclusion
Candice B Biggs stands as a testament to the power of innovation in microbiology and its potential to transform the pharmaceutical landscape. With her groundbreaking patents and collaborative efforts, she continues to make significant strides in the field, paving the way for future advancements in steroid synthesis and microbial applications.