Byung-kwon Choi

Title: Byung-kwon Choi: Innovator in Glycoprotein Production

Introduction

Byung-kwon Choi is a notable inventor based in Hanover, NH (US). He has made significant contributions to the field of biotechnology, particularly in the production of therapeutic glycoproteins. With a total of two patents to his name, Choi's work focuses on enhancing the capabilities of eukaryotic host cells.

Latest Patents

Choi's latest patents revolve around the modification of oligosaccharides in eukaryotic host cells. These modifications allow for the further expression of glycosyltransferases, sugar transporters, and mannosidases. This innovative approach enables the production of human therapeutic glycoproteins. His inventions provide nucleic acid molecules and combinatorial libraries that successfully target and express mammalian enzymatic activities involved in glycosylation. The engineered host cells can express and target desirable genes related to glycosylation, resulting in the creation of N-glycans with a ManGlcNAccore structure. This structure can be further modified to yield human-like glycoproteins, making it a valuable method for producing therapeutic proteins.

Career Highlights

Choi is currently associated with Glycofi, Incorporated, where he continues to advance his research in glycoprotein production. His work has positioned him as a key figure in the biotechnology sector, contributing to the development of innovative solutions for therapeutic applications.

Collaborations

Choi collaborates with esteemed colleagues such as Tillman U Gerngross and Stefan Wildt. Their combined expertise enhances the research and development efforts at Glycofi, Incorporated.

Conclusion

Byung-kwon Choi's innovative work in the field of glycoprotein production showcases his commitment to advancing biotechnology. His patents and collaborations reflect a dedication to improving therapeutic solutions for human health.