Company Filing History:
1 out of 3 
1 out of 164 
Years Active: 2010
Title: Bruno Gilomen: Innovator in Pharmaceutical Chemistry
Introduction
Bruno Gilomen is a notable inventor based in Zurich, Switzerland. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of novel compounds and methods for drug production. His work has implications for the treatment of allergic conditions, showcasing his commitment to advancing medical science.
Latest Patents
Gilomen holds a patent for "Polymorphic forms of olopatadine hydrochloride and methods for producing olopatadine and salts thereof." This invention presents a new polymorphic form of olopatadine hydrochloride, a selective histamine H1-receptor antagonist used to treat ocular symptoms of seasonal allergic conjunctivitis. The patent outlines innovative methods for large-scale production of olopatadine that are cost-effective and reduce impurities. Notably, it eliminates the need for the hazardous base, butyllithium, which has been used in previous methods. The invention also details processes for producing 3-dimethylaminopropyltriphenylphosphonium bromide and its hydrobromide salt, which are essential in the synthesis of olopatadine and its pharmaceutically acceptable salts.
Career Highlights
Throughout his career, Gilomen has worked with prominent organizations, including Azad Pharmaceutical Ingredients AG and the University of Zurich. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to significant advancements in pharmaceutical research.
Collaborations
Some of his notable coworkers include Thomas Bader and Hans-Ulrich Bichsel. Their collaborative efforts have further enriched the research environment and fostered innovation in pharmaceutical development.
Conclusion
Bruno Gilomen's contributions to pharmaceutical chemistry, particularly through his patent on olopatadine hydrochloride, highlight his role as an innovator in the field. His work not only advances medical treatments but also sets a precedent for future research in drug production methods.