Company Filing History:
Years Active: 2002
Title: Brian D. Hamman: Innovator in Optical Probes
Introduction
Brian D. Hamman is a notable inventor based in Poway, California. He has made significant contributions to the field of optical probes and assays. His work focuses on the detection of post-translational modifications, which are crucial for understanding various biological processes.
Latest Patents
Brian D. Hamman holds a patent for his invention titled "Optical probes and assays." This invention provides an optical probe that serves as a sensor for post-translational modifications, such as phosphorylation. The optical probe comprises a polypeptide moiety with a recognition motif for post-translational activity and a protease site coupled to a probe moiety. The modification of the polypeptide by post-translational activity modulates the rate at which a protease cleaves the polypeptide. This modulation is sensed by a measurable change in at least one optical property of the probe upon cleavage. Additionally, the invention includes a recombinant nucleic acid molecule encoding the optical probe, along with a vector and host cell or library of cells that contain the recombinant nucleic acid. The optical probe can be utilized in methods to determine whether a sample contains post-translational modification activity, and it can also identify therapeutic compositions.
Career Highlights
Brian D. Hamman is associated with Aurora Biosciences Corporation, where he continues to advance his research and innovations. His work has implications for therapeutic development and understanding cellular processes.
Collaborations
Some of his notable coworkers include Brian Pollok and Steven M. Rodems. Their collaborative efforts contribute to the innovative environment at Aurora Biosciences Corporation.
Conclusion
Brian D. Hamman's contributions to the field of optical probes and assays highlight his role as an innovator in biotechnology. His patent for optical probes demonstrates the potential for advancements in therapeutic identification and biological research.