Brett Sponseller

Title: Brett Sponseller: Innovator in Influenza Vaccine Development

Introduction

Brett Sponseller is a notable inventor based in Ames, IA (US), recognized for his contributions to the field of immunology. He has been instrumental in developing innovative solutions to combat influenza viruses, showcasing his expertise and dedication to public health.

Latest Patents

Sponseller holds 2 patents, with his latest invention being a Universal Mammalian Influenza Vaccine. This groundbreaking vaccine provides immunogenic compositions that include novel antigens derived from the equine strain of influenza H3N8. The proteins and specific immunogenic domains in this vaccine are effective as primary universal influenza antigens. The disclosed vaccines are highly effective in inducing hemagglutinin (HA) specific antibodies that are reactive to various influenza viruses. They also promote mucosal and systemic immune responses, offering cross-protection against different influenza virus subtypes. In some embodiments, the vaccine is designed to be cross-protective against two or more subtypes of influenza, with or without the use of an adjuvant.

Career Highlights

Brett Sponseller is affiliated with the Iowa State University Research Foundation, Inc., where he continues to advance his research in vaccine development. His work is pivotal in addressing the challenges posed by influenza viruses, contributing to the broader field of infectious disease prevention.

Collaborations

Throughout his career, Sponseller has collaborated with esteemed colleagues, including David Verhoeven and Jessie Dorothy Trujillo. These partnerships have enhanced the scope and impact of his research efforts.

Conclusion

Brett Sponseller's innovative work in developing a universal influenza vaccine highlights his commitment to improving public health through scientific research. His contributions are significant in the ongoing battle against influenza viruses, showcasing the importance of innovation in the field of immunology.