Company Filing History:
Years Active: 2024
Title: Innovator Bettina Budeus: Pioneering Amplification of Double Stranded DNA
Introduction: Bettina Budeus, an accomplished inventor based in Mühlheim, Germany, has made significant contributions to the field of molecular biology. With one notable patent to her name, Budeus is at the forefront of innovative methods for DNA amplification, specifically focusing on double stranded DNA molecules.
Latest Patents: Bettina Budeus holds a patent for "Methods and kits for amplification of double stranded DNA." This patent discloses advanced devices and methods for amplifying double stranded DNA molecules. The process involves end-repair and dA tailing of cell-free DNA (cfDNA) molecules, followed by the attachment of single-stranded hairpin adaptors. This technique creates adaptor-tagged, single-stranded, covalently closed DNA molecules and enhances amplification through both rolling circle amplification and multiple displacement amplification, utilizing a PrimPol enzyme, a DNA polymerase with strand displacement activity accompanied by free nucleotides.
Career Highlights: Budeus's work as an inventor is marked by her innovative approach to DNA research. Her expertise in molecular techniques has placed her at the cutting edge of genetic research and amplification methods, enabling advancements in various scientific applications.
Collaborations: Throughout her career, Bettina Budeus has collaborated with many talented scientists. Notably, she works alongside Ángel Joaquin Picher Serantes, whose contributions have further enriched their shared research endeavors at 4basebio.
Conclusion: Bettina Budeus exemplifies the spirit of innovation in the life sciences sector. With a focus on the amplification of double stranded DNA, her patent is a valuable asset to researchers and institutions seeking to enhance their understanding and utilization of genetic material. Her collaboration with skilled professionals like Ángel Joaquin Picher Serantes continues to pave the way for further advancements in molecular biology.