Barbara J Wiegel

Title: Barbara J Wiegel: Innovator in Recombinant DNA Technology

Introduction

Barbara J Wiegel is a prominent inventor based in Indianapolis, IN (US). She has made significant contributions to the field of biotechnology, particularly in the development of recombinant DNA expression vectors. Her work has implications for the production of important antibiotics.

Latest Patents

Barbara J Wiegel holds a patent for recombinant DNA expression vectors and DNA compounds that encode the isopenicillin N synthetase activity of Aspergillus nidulans. This invention is crucial for producing isopenicillin N synthetase and enhancing the yield of β-lactam-containing antibiotics from antibiotic-producing organisms. The isopenicillin N synthetase gene of A. nidulans can be isolated from plasmid pOGOO4, which is available from the Northern Regional Research Center under the accession number NRRL B-18171. She has 1 patent to her name.

Career Highlights

Barbara is associated with Eli Lilly and Company, where she has been able to apply her expertise in biotechnology. Her work at this leading pharmaceutical company has allowed her to contribute to advancements in antibiotic production.

Collaborations

Throughout her career, Barbara has collaborated with notable colleagues, including Thomas D Ingolia and Stephen W Queener. These partnerships have fostered innovation and progress in her field.

Conclusion

Barbara J Wiegel's contributions to recombinant DNA technology and her work at Eli Lilly and Company highlight her role as a key innovator in biotechnology. Her patent for recombinant DNA expression vectors showcases her commitment to improving antibiotic production.