Company Filing History:
Years Active: 2009-2015
Title: The Innovative Contributions of Barbara Grubb
Introduction
Barbara Grubb is a prominent inventor based in Hillsborough, NC (US). She has made significant contributions to the field of biomedical research, particularly in the study of lung diseases. With a total of three patents to her name, her work has the potential to impact the treatment of chronic obstructive pulmonary disease and cystic fibrosis.
Latest Patents
One of Barbara Grubb's latest patents involves the development of an animal model for chronic obstructive pulmonary disease and cystic fibrosis. This patent describes a nonhuman transgenic mammal whose genome includes a promoter construct linked to a heterologous DNA encoding an epithelial sodium channel β subunit. The promoter construct directs the expression of this subunit in the lung epithelial cells of the animal. As a result, the transgenic mammal exhibits increased lung mucus retention compared to its wild-type counterpart. This innovative model is useful for screening compounds aimed at treating lung diseases such as cystic fibrosis and chronic obstructive pulmonary disease.
Career Highlights
Barbara Grubb is affiliated with the University of North Carolina at Chapel Hill, where she conducts her research. Her work has garnered attention for its potential applications in medical science and therapeutic development.
Collaborations
Some of her notable coworkers include Richard C. Boucher and Wanda Kay O'Neal. Their collaborative efforts contribute to advancing research in the field of lung diseases.
Conclusion
Barbara Grubb's innovative work and patents reflect her dedication to improving health outcomes for individuals suffering from chronic lung conditions. Her contributions to biomedical research are invaluable and continue to pave the way for future advancements in treatment options.