Ayyampudur Palanisamy Prakasham

Title: The Innovative Mind of Ayyampudur Palanisamy Prakasham

Introduction

Ayyampudur Palanisamy Prakasham, stationed in Lucknow, India, is an inventive force known for his contributions in the field of medicinal chemistry. As an inventor with a keen interest in developing compounds with profound therapeutic implications, he has successfully secured a patent that showcases his innovative approach to cancer treatment.

Latest Patents

Ayyampudur's notable patent, titled "Benzylidene Indanones and Processes for Preparation and Use thereof," focuses on a unique class of compounds. This invention relates to benzylidene indanones of general formula 1, which have demonstrated the ability to inhibit tubulin polymerization. A series of compounds, specifically 2-benzylidene-3-(3,4,5-trimethoxyphenyl) indanones, have been synthesized from gallic acid through a precise chemical process. Among these, compound 8 (2-(3,4-Methylenedioxybenzylidine), 3-(3,4,5-trimethoxyphenyl), 4,5,6-trimethoxyindanone) has exhibited remarkable anticancer activity. With a molecular formula of CHO, compound 8 has shown to be safe up to 300 mg/kg body weight in acute oral evaluations with Swiss albino mice, paving the way for further research aimed at identifying potent and cost-effective anticancer agents through in vitro cytotoxicity assays.

Career Highlights

Ayyampudur Palanisamy Prakasham is affiliated with the Council of Scientific & Industrial Research, a beacon of scientific inquiry and innovation in India. His engagement in groundbreaking research signifies his dedication to tackling complex health challenges through scientific innovation.

Collaborations

In his quest for scientific advancement, Ayyampudur has collaborated with esteemed colleagues like Arvind Singh Negi and Ajit Kumar Saxena. Their combined expertise further enriches the innovative projects they undertake, fostering a collaborative environment that promotes extensive research into medicinal compounds.

Conclusion

Ayyampudur Palanisamy Prakasham exemplifies the spirit of innovation in the field of medicinal chemistry. His contributions, particularly through his patent on benzylidene indanones, underline the potential of research and development in addressing serious health issues such as cancer. With a robust educational background and a supportive network of collaborators, Ayyampudur continues to push the boundaries of scientific discovery, ultimately aiming to enhance therapeutic options for patients globally.