Location History:
- New York, NY (US) (2016)
- Bowie, MA (US) (2023)
Company Filing History:
2 out of 1,361 
1 out of 512 
1 out of 559 
Years Active: 2016-2023
Title: Asif M Maroof: Innovator in Neuronal Cell Research
Introduction
Asif M Maroof is a prominent inventor based in Bowie, MA (US). He has made significant contributions to the field of neuronal cell research, holding 2 patents that focus on the differentiation of stem cells into various types of neuronal cells. His work has implications for treating neurodegenerative and neuropsychiatric disorders.
Latest Patents
Maroof's latest patents include innovative methods for producing cortical interneurons and other neuronal cells through the directed differentiation of pluripotent and multipotent cells. One patent describes in vitro methods for generating these cells by manipulating signaling pathways, specifically inhibiting SMAD and Wnt pathways while activating the SHH signaling pathway. This novel approach allows for controlled differentiation of neural progenitor cells into specific neuronal types, including cortical interneurons, hypothalamic neurons, and pre-optic cholinergic neurons. The other patent focuses on isolating a purified population of cortical or striatal immature interneuron progenitor cells, which can be used therapeutically to address conditions related to interneuron function.
Career Highlights
Throughout his career, Asif M Maroof has worked with esteemed institutions such as Cornell University and the Sloan Kettering Institute for Cancer Research. His research has been pivotal in advancing our understanding of neuronal cell differentiation and its applications in medicine.
Collaborations
Maroof has collaborated with notable colleagues, including Stewart A Anderson and Lorenz Studer, contributing to a rich exchange of ideas and advancements in the field of neuroscience.
Conclusion
Asif M Maroof's innovative research and patents in neuronal cell differentiation highlight his significant role in the scientific community. His work not only furthers our understanding of neuronal development but also opens new avenues for therapeutic interventions in neurodegenerative diseases.