Ashok K Tehim

Title: Innovations by Ashok K Tehim

Introduction

Ashok K Tehim is a notable inventor based in Montreal, Canada. He has made significant contributions to the field of chemistry, particularly in the synthesis of optically pure compounds. With a total of 2 patents, his work has implications in the pharmaceutical industry, especially concerning cardiovascular health.

Latest Patents

Tehim's latest patents focus on the synthesis of optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids. The first patent describes a method for synthesizing these acids from an asymmetric .alpha.-hydroxy ester. This innovative approach utilizes a non-nucleophilic lithium amide base under kinetically controlled Claisen conditions. The resulting compounds serve as potent inhibitors of platelet aggregation, working at the level of cyclooxygenase. This invention has potential applications in treating coronary artery diseases and preventing atherosclerosis.

The second patent reiterates the efficient synthesis of optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids, emphasizing the same methodology and its pharmaceutical uses.

Career Highlights

Ashok K Tehim is affiliated with The Ohio State University, where he continues to advance his research and innovation in chemistry. His work has garnered attention for its potential impact on medical treatments and drug development.

Collaborations

Tehim collaborates with Donald T Witiak, contributing to the advancement of their shared research interests.

Conclusion

Ashok K Tehim's innovative work in the synthesis of optically pure compounds showcases his significant contributions to the field of chemistry and its applications in medicine. His patents reflect a commitment to improving health outcomes through scientific research and innovation.