Company Filing History:
Years Active: 1998-1999
Title: Arthur L Haas: Innovator in Biochemistry
Introduction
Arthur L Haas is a notable inventor based in Brookfield, WI (US). He has made significant contributions to the field of biochemistry, particularly through his innovative patents. With a total of 2 patents, Haas has demonstrated his expertise and commitment to advancing scientific knowledge.
Latest Patents
Haas's latest patents include "Cloned nucleotide pyrophosphohydrolase and uses thereof." In this work, he successfully cloned and sequenced the cDNA encoding the 61 kD active fragment of a unique porcine chondrocyte nucleotide pyrophosphohydrolase (NTPPHase) from a porcine chondrocyte library. The research involved hybridizing degenerate oligonucleotides to porcine chondrocyte cDNA and amplifying DNA using the polymerase chain reaction (PCR). The resulting PCR products were utilized to clone the entire open reading-frame for the 61 kD fragment. The length of the cloned cDNA was found to be 2509 bp, predicting the 61 kD fragment to be a 459 amino acid protein. Analysis confirmed the uniqueness of this amino acid sequence, with limited homology detected to known proteins. Additionally, he developed a method for preparing recombinant ubiquitin cross-reactive protein (UCRP), which includes steps to purify UCRP from host cells while preventing proteolytic inactivation.
Career Highlights
Arthur L Haas is associated with the MCW Research Foundation, Inc., where he continues to contribute to research and innovation in biochemistry. His work has implications for various applications in the field, showcasing his dedication to scientific advancement.
Collaborations
Haas has collaborated with notable coworkers, including Jana Narasimhan and Ikuko Masuda, further enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Arthur L Haas is a distinguished inventor whose work in biochemistry has led to significant advancements and innovations. His contributions through patents reflect his commitment to scientific progress and collaboration.