Location History:
- Waltham, MA (US) (2004 - 2005)
- Hanover, NH (US) (2006)
Company Filing History:
Years Active: 2004-2006
Title: The Innovative Contributions of Arie Horowitz
Introduction
Arie Horowitz is an accomplished inventor based in Waltham, Massachusetts, known for her significant contributions to the field of medical technology and biotechnology. With a portfolio of three patents, Horowitz has made strides in understanding and enhancing angiogenesis, a critical process in wound healing and tissue regeneration.
Latest Patents
Horowitz's latest patents focus on the stimulation of angiogenesis through enhanced endothelial expression of syndecan-4 core proteins. These inventions provide tangible methods for stimulating angiogenesis by utilizing a prepared DNA sequence fragment that codes for essential proteins. The approach involves the delivery of this DNA sequence to endothelial cells, which can be performed in both in-vivo and in-vitro conditions using various expression vectors, including plasmids and viruses. By overexpressing core proteins related to heparan sulfate binding, the resulting transfected endothelial cells promote angiogenesis in situ, offering remarkable potential applications for therapeutic interventions.
Career Highlights
Arie Horowitz works at the Beth Israel Deaconess Medical Center, Inc., where she continues her research and development in the field of angiogenesis. Her work is pivotal in exploring new avenues for medical treatments that could significantly improve patient outcomes in various healthcare scenarios.
Collaborations
Throughout her career, Horowitz has collaborated with notable peers such as Michael Simons and Ruediger Volk. These collaborations have enabled her to engage in innovative research projects, further enhancing the impact of her inventions on the scientific community and healthcare practices.
Conclusion
Arie Horowitz’s contributions to the field of medical biotechnology through her innovative patents underline her role as a significant inventor. Her dedication to advancing the understanding of angiogenesis has the potential to reshape therapeutic approaches, making significant strides in medical science that could benefit countless individuals.