Archel M A Ambrosio

Title: Archel M A Ambrosio: Innovator in Biodegradable Matrices for Bone Replacement

Introduction

Archel M A Ambrosio is a notable inventor based in State College, PA (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of innovative materials for bone replacement.

Latest Patents

Ambrosio holds a patent for a groundbreaking invention titled "Poly(organophosphazene) matrices for bone replacement." This patent describes a highly porous three-dimensional biodegradable poly(organophosphazene) matrix that features hydrolytically unstable side chains. The matrix serves as a scaffold for the growth of osteoblast cells, which are crucial for bone formation. In a preferred embodiment, the poly(organophosphazene) includes between 10 and 90% hydrolytically unstable side chains, such as glucosyl, glyceryl, imidazolyl, or ethoxy units. The addition of these side chains enhances the growth rates of cells adhered to the polymer, likely through the uptake and metabolism of the simple sugar or alcohol units.

Career Highlights

Ambrosio's career is marked by his dedication to advancing materials science and its applications in medicine. His innovative work has the potential to improve the outcomes of bone repair and regeneration, making a significant impact on patient care.

Collaborations

Throughout his career, Ambrosio has collaborated with esteemed colleagues, including Cato T Laurencin and Saadiq El-Amin. These partnerships have fostered a rich exchange of ideas and have contributed to the advancement of their shared research goals.

Conclusion

Archel M A Ambrosio is a pioneering inventor whose work in biodegradable matrices for bone replacement exemplifies the intersection of innovation and healthcare. His contributions continue to influence the field and hold promise for future advancements in medical technology.