Archana Brahmandam

Title: Archana Brahmandam: Innovator in Chimeric Receptor Technology

Introduction

Archana Brahmandam is a prominent inventor based in Seattle, WA (US). She has made significant contributions to the field of biotechnology, particularly in the development of modified chimeric receptors for adoptive therapy. Her innovative work has the potential to enhance the efficacy of T cell therapies.

Latest Patents

Archana holds a patent for "Modified chimeric receptors and related compositions and methods." This patent provides chimeric receptors designed for engineering cells for adoptive therapy, including T cells. The invention includes genetically engineered cells where the chimeric receptors are modified in a junction region. These modifications result in a lower binding affinity for human leukocyte antigen (HLA) and reduced immunogenicity. The patent also outlines methods and compositions for engineering and producing cells that express these chimeric receptors, which can lead to improved activity, efficacy, and persistence in therapeutic applications.

Career Highlights

Throughout her career, Archana has worked with notable companies in the biotechnology sector. She has been associated with Juno Therapeutics and Celgene Corporation, where she has contributed her expertise in cell engineering and therapeutic innovations. Her work has been instrumental in advancing the field of adoptive cell therapy.

Collaborations

Archana has collaborated with several professionals in her field, including Lucas James Thompson and Robert F DuBose. These collaborations have further enriched her research and development efforts in chimeric receptor technology.

Conclusion

Archana Brahmandam is a trailblazer in the field of biotechnology, with her innovative patent on modified chimeric receptors paving the way for advancements in adoptive therapy. Her contributions continue to influence the landscape of cell engineering and therapeutic applications.