Ao Ji

Title: Innovations of Inventor Ao Ji

Introduction

Ao Ji is a notable inventor based in Shanghai, China. He has made significant contributions to the field of bioconjugation, particularly in the development of antibody-drug conjugates (ADCs). With a total of two patents to his name, his work has the potential to enhance the efficacy of therapeutic agents.

Latest Patents

Ao Ji's latest patents focus on a process for preparing antibody-drug conjugates with improved homogeneity. The disclosed bio-conjugation process dramatically enhances the homogeneity of ADC products compared to conventional methods. Specifically, the ADCs produced through this innovative process exhibit a content of D0+D8 that is less than 10 wt % and a content of D6 that is also less than 10 wt %. Furthermore, the content of D4 is generally more than 65 wt %, often exceeding 70 wt % and even reaching over 77 wt %. In contrast, conventional conjugation processes typically yield ADCs with D4 content that is normally less than 40 wt %.

Career Highlights

Throughout his career, Ao Ji has worked with prominent companies in the biotechnology sector. Notable among these are Wuxi Biologics Ireland Limited and Wuxi Xdc Singapore Private Limited. His experience in these organizations has contributed to his expertise in the field of bioconjugation and ADC development.

Collaborations

Ao Ji has collaborated with several professionals in his field, including Chuchu Sun and Wenxu He. These collaborations have likely facilitated the advancement of his research and innovations.

Conclusion

In summary, Ao Ji is an accomplished inventor whose work on antibody-drug conjugates has the potential to significantly impact the field of biomedicine. His innovative processes and collaborations highlight his commitment to advancing therapeutic technologies.