Company Filing History:
Years Active: 1991-2004
Title: Biography of Antonio Bernad
Introduction
Antonio Bernad is a prominent inventor based in Madrid, Spain. He has made significant contributions to the field of molecular biology, particularly in the area of DNA polymerases and their applications in genetic research. With a total of four patents to his name, Bernad has established himself as a key figure in the scientific community.
Latest Patents
Among his latest patents is the innovative use of beta recombinase in eukaryotic cells, especially for transgenic work. Another notable patent involves an improved method for determining the nucleotide base sequence of a DNA molecule. This method employs a φ-29 type DNA polymerase modified to have reduced or no exonuclease activity. The process includes annealing the DNA molecule with a primer molecule, incubating the mixture with deoxynucleoside triphosphates and DNA synthesis terminating agents, and separating the DNA products according to size. This advancement allows for a more accurate determination of the nucleotide base sequence of DNA.
Career Highlights
Antonio Bernad has worked with esteemed institutions, including the Consejo Superior de Investigaciones Científicas, where he has contributed to various research projects. His work has been instrumental in advancing the understanding of DNA polymerases and their applications in genetic engineering.
Collaborations
Throughout his career, Bernad has collaborated with notable scientists such as Luis Blanco and Margarita Salas. These collaborations