Anthony Nicola

Title: Innovations by Anthony Nicola in Herpes Simplex Virus Research

Introduction

Anthony Nicola is a notable inventor based in Philadelphia, PA (US). He has made significant contributions to the field of virology, particularly in the development of innovative solutions for preventing herpes simplex virus infections. With a total of 2 patents, his work is recognized for its potential impact on public health.

Latest Patents

One of Anthony Nicola's latest patents focuses on "Herpes simplex virus glycoprotein D variants." This invention provides variant HSV-1 glycoprotein D and HSV-2 glycoprotein D molecules that are capable of preventing infection of cells by herpes simplex virus types 1 and/or 2. The patent also includes novel purified and isolated polynucleotides encoding these variant gD molecules. Specifically, the invention contemplates HSV gD-1 and gD-2 region IV variants or fragments thereof. The preferred variant molecule, gD-1(.DELTA.290-299t), is produced through recombinant expression in Sf9 cells. This molecule includes a fusion protein that incorporates the signal peptide of honeybee melittin and modifications to the Patton strain HSV-1 gD. The administration of these gD variant molecules is intended for preventing HSV infection and ameliorating the pathological sequelae associated with it.

Career Highlights

Anthony Nicola is associated with Competitive Technologies, Inc., where he continues to advance his research and innovations. His work has garnered attention for its potential applications in therapeutic settings.

Collaborations

He collaborates with esteemed colleagues such as Gary H Cohen and Roselyn J Eisenberg, contributing to a dynamic research environment that fosters innovation.

Conclusion

Anthony Nicola's contributions to the field of herpes simplex virus research exemplify the importance of innovation in addressing public health challenges. His patents reflect a commitment to developing effective solutions for preventing viral infections.