Company Filing History:
11 out of 656 
4 out of 15,475 
3 out of 389 
Years Active: 1986-2006
Title: The Innovative Journey of Anthony J. Brake
Introduction
Anthony J. Brake, a notable inventor based in Berkeley, California, has made significant contributions to the field of biomedicine. With a remarkable portfolio of 14 patents, his work primarily revolves around the capsaicin receptor and its related polypeptides. These innovations have far-reaching implications for the diagnosis and treatment of various human diseases and painful syndromes.
Latest Patents
Brake’s latest patents focus on nucleic acid sequences encoding capsaicin receptors and their related polypeptides. His inventions highlight vanilloid receptor polypeptides, specifically the capsaicin receptor subtypes VR1 and VR2 (VRRP-1), along with the corresponding encoding polynucleotide sequences. The invention also features expression vectors and host cells containing these polynucleotides. Furthermore, Brake has developed transgenic animals exhibiting altered capsaicin receptor expression, which can arise from the introduction of either wild-type or modified capsaicin receptor-encoding polynucleotide sequences. Notably, his inventions also include methods for producing antibodies that specifically bind to capsaicin receptor polypeptides, as well as methods for utilizing the capsaicin receptor for screening candidate agents that may act as agonists or antagonists. Overall, his work contributes valuable methods for the diagnosis and treatment of various ailments using the capsaicin receptor.
Career Highlights
Throughout his career, Anthony J. Brake has worked with prestigious organizations that include Chiron Corporation and the University of California. His affiliations with these institutions showcase his commitment to advancing scientific knowledge and innovation in the area of receptor biology.
Collaborations
Brake has had the opportunity to collaborate with prominent scientists in the field, including David J. Julius and Philip J. Barr. Their collective efforts have further propelled advancements in understanding the roles of capsaicin receptors in human health.
Conclusion
In summary, Anthony J. Brake's career as an inventor has been marked by significant contributions to the biomedical field through his extensive research and patent portfolio. His innovative work on capsaicin receptors not only enhances our understanding of pain mechanisms but also opens new avenues for therapeutic intervention. Brake’s collaborations and experiences at leading organizations underscore the importance of teamwork and shared knowledge in driving innovation forward.