Company Filing History:
Years Active: 2011-2012
Title: Innovations by Anthony D Marinov in Immunomodulation
Introduction
Anthony D Marinov is an accomplished inventor based in Munhall, PA (US). He has made significant contributions to the field of immunology, particularly in the modulation of inflammatory conditions. With a total of 2 patents, his work focuses on the therapeutic potential of Follistatin-like Protein-1 (FSTL-1).
Latest Patents
One of Marinov's latest patents is centered on the immunomodulation of inflammatory conditions utilizing Follistatin-like Protein-1 and agents that bind thereto. FSTL-1 is a secreted glycoprotein that has been identified as a proinflammatory mediator. The invention outlines compositions and methods for using agents that bind to FSTL-1 to modulate various types of inflammation, including autoimmune diseases. Inhibitors and antagonists of FSTL-1, particularly antibodies or antibody fragments, are proposed for treating conditions related to inflammation, such as arthritis. Furthermore, Marinov's research indicates that FSTL-1 plays a role in the Th17 pathway, leading to the development of agents that can modulate the generation of Th17 cells. This has implications for delaying the development of diseases associated with undesired Th17 cell production. Additionally, the invention explores the potential of FSTL-1 in cancer treatment, providing compositions and methods for using FSTL-1 to delay the development of or treat cancer.
Career Highlights
Anthony D Marinov is affiliated with the University of Pittsburgh, where he conducts his research and development work. His innovative approaches have garnered attention in the scientific community, contributing to advancements in the understanding and treatment of inflammatory conditions.
Collaborations
Marinov has collaborated with notable colleagues, including Raphael Hirsch and David C Wilson, to further his research endeavors.
Conclusion
Anthony D Marinov's work in immunomodulation through Follistatin-like Protein-1 represents a significant advancement in the treatment of inflammatory conditions and cancer. His contributions continue to influence the field of immunology and offer hope for new therapeutic strategies.