Company Filing History:
Years Active: 2022
Title: Innovator Spotlight: Anna Cereseto from Trento, Italy
Introduction
Anna Cereseto is a distinguished inventor based in Trento, Italy, recognized for her significant contribution to the field of genetic engineering. With a focus on advancing genome editing technologies, she has made strides in enhancing the accuracy of gene editing tools, specifically Cas9 variants.
Latest Patents
Anna Cereseto holds a notable patent related to her innovative work: "High-fidelity CAS9 variants and applications thereof." This invention addresses the challenges associated with the unspecific genomic cleavages of the conventional Cas9 (SpCas9). By employing a yeast-based assay, her invention allows for the simultaneous evaluation of on-target and off-target activities towards engineered genomic targets. Through random mutagenesis of the Red-II domain, Anna identified SpCas9 variants with improved on/off cleavage ratios. The standout variant, dubbed evoCas9, exhibited a significant enhancement in fidelity over previously designed alternatives, marking a crucial development for the future of gene editing.
Career Highlights
Anna is associated with the University of Trento, where she collaborates with fellow researchers to push the boundaries of genetic engineering. Her dedication to research and innovation has led to this impactful patent, underlining her ability to address critical challenges in the field.
Collaborations
Throughout her career, Anna has collaborated with esteemed colleagues including Antonio Casini and Gianluca Petris. These partnerships have facilitated valuable exchanges of ideas and expertise, contributing to the successful realization of her innovative projects.
Conclusion
Anna Cereseto exemplifies the spirit of innovation in contemporary science. Her work not only enhances the field of genetic engineering but also sets the stage for future advancements in gene editing technologies. With a commitment to developing more accurate tools for genomic modifications, Anna continues to pave the way for researchers and practitioners in this rapidly evolving domain.