Location History:
- Surrey, GB (2002)
- Richmond, GB (2016)
Company Filing History:
Years Active: 2002-2016
Title: Innovations of Andrew John Timothy George
Introduction
Andrew John Timothy George is a notable inventor based in Richmond, GB. He has made significant contributions to the field of biomedical engineering, particularly in the area of anticoagulant proteins. With a total of 2 patents, his work focuses on enhancing organ transplantation outcomes.
Latest Patents
One of his latest patents is an anticoagulant fusion protein anchored to the cell membrane. This invention relates to the inhibition of blood coagulation, especially during organ rejection, and specifically addresses the inhibition of delayed vascular rejection. The invention provides anticoagulant proteins that are anchored to cell membranes. The anticoagulant function is preferably provided by heparin, antithrombin, hirudin, TFPI, tick anticoagulant peptide, or a snake venom factor. These anticoagulant proteins are designed to prevent constitutive expression at the cell surface. In particular, the expression at the cell surface is regulated according to cell activation, for instance, by targeting the protein to a suitable secretory granule. The expression of these proteins renders cells, tissues, and organs less vulnerable to rejection after transplantation, such as after xenotransplantation.
Career Highlights
Throughout his career, Andrew has worked with prominent organizations, including Imperial College Innovations Limited and Imperial Innovations Limited. His innovative approaches have contributed to advancements in medical technology and organ transplantation.
Collaborations
Andrew has collaborated with notable professionals in his field, including Kristian Riesbeck and Anthony Dorling. These collaborations have further enhanced the impact of his inventions.
Conclusion
Andrew John Timothy George is a distinguished inventor whose work in anticoagulant proteins has the potential to revolutionize organ transplantation. His contributions are vital in addressing the challenges of organ rejection, making significant strides in medical science.