Company Filing History:
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Years Active: 1995-2000
Title: **Andrew J. Ghio: Innovator in Pulmonary Health**
Introduction
Andrew J. Ghio is a notable inventor based in Durham, North Carolina, recognized for his contributions to medical innovations. With a total of five patents to his name, he has dedicated his expertise to developing groundbreaking methods and medicants for treating chronic pulmonary inflammation and other inflammatory disorders.
Latest Patents
Among his latest developments is a patent addressing the treatment of chronic pulmonary inflammation. This patent details a method and medicant for inhibiting the activation of nuclear transcription factor NF-kappa B. The invention involves administering an effective amount of a specific compound, where R is ethylene and R' ranges from C4 to C14 straight-chain or branched alkyl. This medicant is ideally administered through aerosolization into the mammalian respiratory system and may also be applied to the skin. In particular, the formulation is designed to include a physiologically acceptable carrier, such as buffered saline or petroleum-based ointments, and may incorporate anti-inflammatory steroids. Additionally, it offers a method for treating cutaneous inflammatory disorders by inhibiting the secretion of pro-inflammatory cytokines like TNF, IL-1, IL-6, IL-8, and the growth factor GM-CSF.
Career Highlights
Andrew Ghio's career includes significant roles at renowned institutions, including Duke University and the Charlotte Hospital Authority. His work has facilitated crucial advancements in the field of pulmonary health, demonstrating his commitment to improving patient outcomes through innovative research and development.
Collaborations
Throughout his professional journey, Andrew has collaborated with esteemed colleagues, including Thomas P. Kennedy and Claude A. Piantadosi. Their teamwork has contributed to the successful development and refinement of his patents, highlighting the importance of collaboration in the field of medical innovation.
Conclusion
Andrew J. Ghio exemplifies the spirit of innovation through his research and advancements in medical therapies. His patents not only address critical health issues but also pave the way for future developments in the treatment of pulmonary and cutaneous inflammatory disorders. Through his work, he continues to make a meaningful impact on the medical community and patient care.