Location History:
- Milton Keynes, GB (1989)
- Horsforth, Leeds LS18 5RW, GB (2002)
Company Filing History:
2 out of 12 Years Active: 1989-2002
Title: Andrew J Barker: Innovator in Antibacterial Compounds
Introduction
Andrew J Barker is a notable inventor based in Milton Keynes, GB, with a focus on developing innovative pharmaceutical solutions. He has contributed to the field significantly, holding a total of two patents to his name. His research is pivotal in the fight against bacterial infections, addressing a critical need in healthcare.
Latest Patents
Among his latest patents, Barker has developed a series of compounds known as 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives. These compounds are structured to possess antibacterial effects, with potential applications in treating infections. Specifically, his patent details a compound of formula I, where R.sup.1 is an alkyl group that may include various substituents, along with esters at the 2-carboxy group or the 8-hydroxy group, or possibly both. This compound is synthesized by reacting specific precursor compounds with an amine, showcasing Barker’s innovative approach in chemical synthesis.
Additionally, his work includes antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives, where variations of R.sup.1 may represent hydrogen or short-chain alkyl groups. These derivatives exhibit significant antibacterial and beta-lactamase inhibiting activities, marking a substantial advancement in antibiotic development.
Career Highlights
Andrew J Barker has made noteworthy contributions while working at Hoechst (UK) Limited. His efforts focus on the design and synthesis of novel compounds aimed at combating bacterial resistance, which is a growing concern in modern medicine. His patents not only reflect his inventive capabilities but also indicate his commitment to enhancing therapeutic options available for patients.
Collaborations
Throughout his career, Barker has collaborated with esteemed professionals such as Michael D Cooke and Nicholas I Carruthers. These collaborative efforts have enriched his research endeavors, combining diverse expertise to push the boundaries of pharmaceutical innovation.
Conclusion
In conclusion, Andrew J Barker stands as a prominent figure in the realm of antibacterial compound development. His patents represent vital steps toward innovative treatments in healthcare. With ongoing collaboration and a commitment to research, Barker continues to contribute significantly to the world of pharmaceuticals.