Andrew Bohm

Title: Andrew Bohm: Innovator in Anthrax Pathogenesis Research

Introduction

Andrew Bohm is a notable inventor based in Stoneham, MA (US). He has made significant contributions to the field of microbiology, particularly in understanding anthrax pathogenesis. His innovative work has led to the development of methods and compositions that could potentially aid in combating bacterial infections.

Latest Patents

Andrew Bohm holds a patent for "Methods and compositions relating to anthrax pathogenesis." This patent details the crystallization of the structures of Edema Factor alone and Edema Factor bound to calmodulin without substrate, determined through x-ray crystallography. Based on these crystal structures, he presents a method for assaying inhibitors of infection by bacteria. This method involves obtaining a potential inhibitor, a calmodulin-activated adenylyl cyclase exotoxin, and calmodulin, followed by admixing these components and assaying to determine whether the potential inhibitor inhibits the production of cAMP by the exotoxin.

Career Highlights

Throughout his career, Andrew Bohm has worked with prestigious institutions, including the University of Chicago and Boston Biomedical Research Institute. His research has focused on the mechanisms of bacterial infections and the development of therapeutic strategies.

Collaborations

Andrew has collaborated with various professionals in his field, including Wei-Jen Tang, enhancing the scope and impact of his research.

Conclusion

Andrew Bohm's innovative work in anthrax pathogenesis exemplifies the critical role of inventors in advancing scientific knowledge and developing potential therapeutic solutions. His contributions continue to influence the field of microbiology and public health.