Company Filing History:
Years Active: 2020-2021
Title: Innovations of Andreas Mueller-Hermann in Nucleic Acid Amplification
Introduction
Andreas Mueller-Hermann is a notable inventor based in Munich, Germany. He has made significant contributions to the field of nucleic acid amplification, holding three patents that showcase his innovative methods. His work focuses on enhancing the efficiency of nucleic acid synthesis and detection.
Latest Patents
One of his latest patents is a process for the enzymatic synthesis and amplification of nucleic acids. This method utilizes a target sequence-specific activator oligonucleotide to amplify a predefined nucleic acid chain. The activator oligonucleotide facilitates the separation of re-synthesized complementary primer extension products through strand displacement. This allows a new primer oligonucleotide to attach to the template strand, initiating a new primer extension reaction. The resulting primer extension products serve as templates, leading to exponential amplification. The efficiency of this process is notably higher when there is a perfect match between the activator oligonucleotide and the target sequence. Mismatches can lead to less efficient amplification, which can be measured and compared.
Another significant patent involves a method for indicating the progress of nucleic acid amplification. This method also relies on the use of a target sequence-specific activator oligonucleotide. The detection system employed in this method allows for the monitoring of amplification progress, ensuring accurate results.
Career Highlights
Andreas Mueller-Hermann is currently associated with Agct GmbH, where he continues to develop innovative solutions in the field of molecular biology. His expertise in nucleic acid amplification has positioned him as a key figure in this area of research.
Collaborations
He has collaborated with notable colleagues such as Dmitry Cherkasov and Norbert Basler, contributing to advancements in their shared field of expertise.
Conclusion
Andreas Mueller-Hermann's work in nucleic acid amplification represents a significant advancement in molecular biology. His innovative patents and ongoing research continue to influence the field positively.