Prague, Czechia

Andrea Popelova

USPTO Granted Patents = 1 



Average Co-Inventor Count = 4.0

ph-index = 1

Forward Citations = 2(Granted Patents)


Company Filing History:


Years Active: 2018

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1 patent (USPTO):Explore Patents

Title: Andrea Popelova: Innovator in Anti-Obesity Research

Introduction

Andrea Popelova is a notable inventor based in Prague, Czech Republic. She has made significant contributions to the field of biochemistry, particularly in the development of anti-obesity agents. Her innovative work focuses on lipidated peptides that have the potential to revolutionize obesity treatment.

Latest Patents

Andrea Popelova holds a patent for "Lipidated peptides as anti-obesity agents." This patent describes lipidated peptides, which are analogs of the prolactin-releasing peptide forms, PrRP31 and PrRP20. These compounds are recognized for their anorexigenic properties, which help reduce food intake and function effectively in the brain after being administered peripherally. The lipidated analogs, modified at the N-terminus with myristic or palmitic acids, exhibit a high affinity for the GPR10 receptor in both rat pituitary cell lines and human-transfected CHO cell lines. In studies, these peptides have demonstrated a significant decrease in food intake in fasted mice, showing stronger and longer-lasting effects compared to naturally administered PrRP31.

Career Highlights

Andrea Popelova is affiliated with the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences. Her research has positioned her as a key figure in the exploration of neuropeptides and their applications in combating obesity. With her innovative approach, she has contributed to the understanding of how lipidation can enhance the effectiveness of anorexigenic neuropeptides.

Collaborations

Throughout her career, Andrea has collaborated with esteemed colleagues, including Lenka Maletinska and Blanka Zelezna. These partnerships have fostered a collaborative environment that enhances research outcomes and drives innovation in the field.

Conclusion

Andrea Popelova's work in developing lipidated peptides as anti-obesity agents showcases her commitment to advancing scientific knowledge and improving health outcomes. Her contributions are paving the way for new treatments in obesity management.

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