Company Filing History:
Years Active: 2013-2025
Title: Innovations of Anders Olof Herman Nygren
Introduction
Anders Olof Herman Nygren is a notable inventor based in San Diego, California. He has made significant contributions to the field of molecular biology and genetics, holding a total of 11 patents. His work primarily focuses on methods for detecting and quantifying minor nucleic acid species in complex mixtures.
Latest Patents
One of his latest patents is a multiplexed method for the identification and quantitation of minor alleles and polymorphisms. This innovative method provides products and processes for detecting the presence or absence of minor nucleic acid species in a sample that contains a mixture of minor and major nucleic acid species. The method involves amplifying the mixture and extending the resulting amplicons using chain-terminating reagents and extension primers that specifically hybridize to the amplicons. By skewing the concentrations of the chain-terminating reagents, the detection limit for minor nucleic acid species is significantly improved. Additionally, the signals generated from the extension product of the major nucleic acid species amplicon can serve as a positive control, allowing for the quantification of minor nucleic acid species relative to the major nucleic acid species in the mixture.
Career Highlights
Throughout his career, Nygren has worked with prominent companies in the biotechnology sector, including Agena Bioscience, Inc. and Sequenom, Inc. His expertise in molecular diagnostics has positioned him as a key figure in the development of innovative technologies in this field.
Collaborations
Nygren has collaborated with notable professionals such as Mathias Ehrich and Taylor Jacob Jensen, contributing to advancements in genetic research and diagnostics.
Conclusion
Anders Olof Herman Nygren's contributions to the field of molecular biology through his patents and collaborations highlight his role as an influential inventor. His innovative methods for detecting nucleic acid species continue to impact genetic research and diagnostics.