Location History:
- Philadelphia, PA (US) (1998)
- Narbeth, PA (US) (1999)
- Narberth, PA (US) (2000 - 2003)
Company Filing History:
2 out of 528 
1 out of 2 
1 out of 9 Years Active: 1998-2003
Title: **Allyson D Cole-Strauss: Innovator in Mutational Vectors**
Introduction
Allyson D Cole-Strauss is a distinguished inventor based in Narberth, Pennsylvania, known for her significant contributions to the field of genetic engineering. With a remarkable portfolio of four patents, her work focuses on advanced mutational vectors that have implications in various biotechnological applications.
Latest Patents
Cole-Strauss' latest patents include innovations in both chimeric and non-chimeric mutational vectors. The patent titled "Eukaryotic Use of Improved Chimeric Mutational Vectors" details a novel methodology utilizing recombinagenic oligonucleotides within a cell-free system. This system notably converts a mutant kan gene to recover the resistant phenotype in transformed MutS and RecA deficient bacteria. Her innovative Heteroduplex Mutational Vector has shown enhanced activity compared to previous mutational vectors due to the incorporation of a nuclease resistant oligonucleotide.
Additionally, her patent "Eukaryotic Use of Non-Chimeric Mutational Vectors" presents a method involving Duplex Mutational Vectors that are effective substrates for eukaryotic enzymes. This vector is protected from 3' exonuclease attack in eukaryotic cells, further showcasing her advancements in the field.
Career Highlights
Throughout her career, Allyson has worked with renowned institutions, including Thomas Jefferson University and Kimeragen, Inc. Her research has not only contributed to the scientific community but has also paved new paths in genetic engineering technology.
Collaborations
Cole-Strauss has collaborated with notable coworkers such as Eric B Kmiec and Kyonggeun Yoon. These collaborations have enriched her research and strengthened her work's impact on the field of genetic mutation and biotechnology.
Conclusion
Allyson D Cole-Strauss exemplifies the spirit of innovation in the realm of genetic engineering. Her patents on mutational vectors provide significant advancements that have the potential to revolutionize gene therapy and biotechnology practices. With her ongoing contributions, she continues to inspire future generations of inventors and researchers.