Alexander Pearlman

Title: Innovations and Contributions of Alexander Pearlman

Introduction

Alexander Pearlman is a notable inventor based in New York, NY (US). He has made significant contributions to the field of cancer research, particularly in understanding the mechanisms of DNA repair and cancer metastasis. With a total of 5 patents, his work has the potential to impact cancer diagnostics and treatment.

Latest Patents

Among his latest patents is a method for determining the functional activity of DNA double strand break repair pathway molecules. This innovation assesses the germline risk of cancer, particularly focusing on heritable mutations in the BRCA1 and BRCA2 genes. These mutations are known to increase the risk of breast, ovarian, and other cancers. The patent describes flow cytometry-based functional variant analyses (FVAs) that can distinguish high-risk BRCA1 mutations from low-risk controls. Another significant patent involves a robust genomic predictor of breast and lung cancer metastasis. This method determines the risk of metastasis by analyzing the number of copies per cell of specific genes in a sample from the subject.

Career Highlights

Alexander Pearlman has worked at the Albert Einstein College of Medicine, where he has contributed to groundbreaking research in cancer genetics. His work has been instrumental in developing methods that enhance the understanding of cancer risks associated with genetic mutations.

Collaborations

Throughout his career, Pearlman has collaborated with esteemed colleagues such as Harry Ostrer and Johnny C Loke. These collaborations have further enriched his research and innovations in the field.

Conclusion

Alexander Pearlman's contributions to cancer research through his patents and collaborations highlight his role as a significant inventor in the medical field. His work continues to pave the way for advancements in cancer diagnostics and treatment strategies.