Company Filing History:
Years Active: 1996-1998
Title: Innovations of Alexander P Vrinzen
Introduction
Alexander P Vrinzen is a notable inventor based in Meerssen, Netherlands. He has made significant contributions to the field of crystallization, particularly in the production of aspartame. With a total of 3 patents, his work has advanced methods for creating high-quality crystalline forms of this widely used sweetener.
Latest Patents
Vrinzen's latest patents focus on innovative methods for crystallizing α-L-aspartyl-L-phenylalanine methyl ester, commonly known as aspartame. One of his patents describes an improved method for crystallization from an aqueous solution using conductive cooling while avoiding turbulence. This method ensures that crystallization occurs at a temperature not lower than 10°C, utilizing at least 0.1% by weight of a C3-8 ketone. The careful selection of ketone and temperature allows for a homogeneous solvent system at the start of crystallization, resulting in an open drainable network of aspartame crystals.
Another patent outlines a method for crystallizing aspartame that involves providing dispersed droplets of a fluid mixture containing aspartame and water, along with a water-immiscible fluid zone. The droplets are passed through this zone under effective temperature and dispersive conditions, leading to a state of initial relative supersaturation of aspartame. This process culminates in the collection of droplets in a static zone, forming a slurry of crystalline aspartame.
Career Highlights
Vrinzen is associated with Holland Sweetener Company, V.o.f., where he has applied his expertise in crystallization techniques. His work has not only contributed to the efficiency of aspartame production but has also enhanced the quality of the final product.
Collaborations
Throughout his career, Vrinzen has collaborated with notable colleagues, including Marinus P Rijkers and Antoon G Toussaint. These partnerships have fostered innovation and development in the field of sweetener production.
Conclusion
Alexander P Vrinzen's contributions to the crystallization of aspartame have significantly impacted the industry. His innovative methods and collaborative efforts continue to advance the field, ensuring the production of high-quality sweeteners.