Company Filing History:
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1 out of 1 Years Active: 2001-2017
Title: Inventor Profile: Alexander Olek
Introduction
Alexander Olek is a prolific inventor based in Berlin, Germany, known for his significant contributions to the field of genomic research. With a total of 12 patents to his name, Olek has been at the forefront of developing innovative methods that improve our understanding of DNA methylation and nucleic acid amplification.
Latest Patents
Among Olek's latest patents is a groundbreaking method for determining the degree of methylation of defined cytosines in genomic DNA within the sequence context of 5'-CpG-3′. This method enables researchers to chemically treat genomic DNA to convert cytosine bases to uracil without affecting 5-methylcytosine bases. Through a series of amplification and detection steps, this technique allows for precise analysis of methylation levels, providing crucial insights into gene regulation and expression.
Another noteworthy patent involves a method for the simultaneous amplification of multiple sequences during a PCR reaction. This innovative approach uses primer oligonucleotides with dual domains, enhancing the efficiency of nucleic acid amplification and marking. By employing a polymerase reaction and a labeled primer that binds to the generic domain, this method facilitates comprehensive analysis of amplificates, further contributing to advancements in genetic research.
Career Highlights
Throughout his career, Alexander Olek has held positions in notable companies, such as Epigenomics AG and Biopsytec GmbH. His work in these organizations has allowed him to develop and refine his patented techniques, assisting the scientific community in several vital areas of genomic research.
Collaborations
Olek has collaborated with esteemed colleagues, including Kurt Berlin and Christian Piepenbrock. Their collective expertise has helped enhance the impact of Olek's inventions and drive innovations in the field.
Conclusion
Alexander Olek's contributions to genomic research, reflected in his 12 patents, exemplify the power of innovation and collaboration in science. His pioneering methods for DNA methylation analysis and nucleic acid amplification continue to influence the landscape of genetic research, paving the way for future advancements in the field.