Company Filing History:
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1 out of 832,961 Years Active: 2000-2002
Title: The Innovations of Alex E MacKenzie
Introduction
Alex E MacKenzie is a notable inventor based in Ottawa, Canada. He has made significant contributions to the field of genetics, particularly in understanding neurodegenerative disorders. With a total of 2 patents, his work has had a profound impact on medical research and treatment options.
Latest Patents
MacKenzie's latest patents include groundbreaking research on the neuronal apoptosis inhibitor protein gene sequence and mutations causative of spinal muscular atrophy. This research has mapped the gene for the autosomal recessive neurodegenerative disorder Spinal Muscular Atrophy to a specific region of chromosome 5. The gene encodes a protein that shares homology with apoptosis inhibitor proteins found in viruses, leading to its designation as a neuronal apoptosis inhibitor protein (NAIP). Notably, a deletion in the NAIP domain was identified in individuals with Types I, II, and III Spinal Muscular Atrophy, which was absent in the normal non-SMA population.
Career Highlights
Throughout his career, MacKenzie has worked with esteemed institutions such as the University of Ottawa and the Research Development Corporation of Japan. His research has not only advanced scientific understanding but has also opened new avenues for therapeutic interventions.
Collaborations
Some of his notable coworkers include Robert G Korneluk and Natalie Roy, who have contributed to his research endeavors and innovations.
Conclusion
Alex E MacKenzie stands out as a significant figure in the field of genetics, with his innovative patents paving the way for advancements in the understanding and treatment of spinal muscular atrophy. His contributions continue to inspire future research in neurodegenerative disorders.