Location History:
- Essex Junction, VT (US) (2011)
- Essex, VT (US) (2018)
Company Filing History:
Years Active: 2011-2018
Title: Albert Van Der Vliet: Innovator in Protein Detection and Inhibition
Introduction
Albert Van Der Vliet is a notable inventor based in Essex, Vermont, who has made significant contributions to the field of biochemistry. He holds 2 patents that focus on innovative methods for detecting oxidized proteins and developing inhibitors for dual oxidase 1 (DUOX1). His work has implications for treating conditions such as asthma and understanding protein modifications.
Latest Patents
One of Van Der Vliet's latest patents is centered around covalent inhibitors of dual oxidase 1 (DUOX1). This invention relates to inhibitors that can be applied to subjects at risk for asthma or other related conditions. The inhibitors can be delivered through various techniques, including pulmonary or topical methods. They may include peptides or other moieties with reactive electrophiles that target specific residues within DUOX1 to inhibit its activity. Examples of suitable inhibitors include hydroxynonenal, curcumin, and sulforaphane, among others.
Another significant patent involves the detection of nitrosylated proteins. This invention provides systems and methods for determining oxidized proteins, including S-nitrosylated proteins. The methods can be utilized both in vitro and in vivo, allowing for spatial determination of oxidized proteins within cells and tissues. The invention includes kits that comprise detection entities and various agents necessary for the detection process.
Career Highlights
Albert Van Der Vliet is affiliated with the University of Vermont and State Agricultural College, where he conducts his research and development work. His academic background and professional endeavors have positioned him as a key figure in the study of protein interactions and their implications in health.
Collaborations
Van Der Vliet has collaborated with notable colleagues, including Yvonne M Janssen and Karina Ckless. These collaborations have likely contributed to the advancement of his research and the successful development of his patents.
Conclusion
Albert Van Der Vliet's innovative work in the field of biochemistry, particularly in the detection of oxidized proteins and the development of inhibitors, showcases his significant contributions to science. His patents reflect a commitment to advancing medical research and improving treatment options for various conditions.