Company Filing History:
Years Active: 2019
Title: Innovations of Albert J Keung in DNA Methylation
Introduction
Albert J Keung is a prominent inventor based in Raleigh, NC (US). He has made significant contributions to the field of genetic engineering, particularly in the area of DNA methylation. His innovative work has the potential to advance our understanding of gene regulation and epigenetics.
Latest Patents
Albert J Keung holds a patent for an "Integrated system for programmable DNA methylation." This patent describes engineered systems and methods for establishing DNA adenine methylation at specific genomic locations. The invention utilizes DNA adenine methylation as an artificial chemical 'handle' on the genome. The systems and methods allow for placing the handle on specific genomic locations, as well as molecular technologies to bind, spatially spread, and maintain the handle. The described systems comprise three functional modules that mediate m6A operations: (1) a synthetic initiator module to place m6A at specific genomic sites; (2) a synthetic readout module to program m6A recognition and m6A-dependent transcriptional logic; and (3) a propagation module that implements 'read-write,' a mechanism proposed to underlie chromatin spreading and epigenetic maintenance across cellular systems. He has 1 patent to his name.
Career Highlights
Albert J Keung is affiliated with Boston University, where he continues to push the boundaries of research in genetic engineering. His work has garnered attention for its innovative approach to manipulating DNA methylation, which is crucial for understanding gene expression and regulation.
Collaborations
He has collaborated with notable researchers in the field, including Ahmad S Khalil and Minhee Park. These collaborations have further enriched his research and contributed to advancements in the understanding of DNA methylation.
Conclusion
Albert J Keung's contributions to the field of DNA methylation represent a significant advancement in genetic engineering. His innovative systems and methods have the potential to revolutionize our approach to gene regulation and epigenetics.