Location History:
- Chuo-ku, JP (2008)
- Minato-ku, JP (2010)
- Tokyo, JP (2006 - 2012)
Company Filing History:
7 out of 35,658 
1 out of 4 Years Active: 2006-2012
Title: Akira Tsugita: Innovator in Peptide Analysis
Introduction
Akira Tsugita is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of peptide analysis, holding a total of 7 patents. His innovative methods have advanced the understanding and analysis of amino acid sequences in peptides.
Latest Patents
One of Akira Tsugita's latest patents is a method for analyzing the C-terminal amino acid sequence of a peptide using mass spectrometry. This invention provides a technique for successively releasing the C-terminal amino acids of a peptide while minimizing undesirable side reactions, such as the cleavage of peptide bonds in intermediate positions. The method involves subjecting a dry sample of a long amino acid peptide to an N-acylation treatment. By utilizing a reaction reagent that combines an alkanoic acid anhydride with a small amount of a perfluoroalkanoic acid, the successive release of C-terminal amino acids is conducted under mild conditions. Following this, a hydrolysis treatment is applied, and selective fragmentization at the site of arginine residue is performed through trypsin digestion. The molecular weight decreases of the C-terminal side fragments are then measured using a MALDI-TOF-MS apparatus, allowing for the identification of the C-terminal amino acid sequence of the peptide sample.
Career Highlights
Throughout his career, Akira Tsugita has worked with notable companies, including NEC Corporation and Tokyo Rikakikai Co., Ltd. His work in these organizations has contributed to his expertise in peptide analysis and mass spectrometry.
Collaborations
Some of his coworkers include Kenji Miyazaki and Kenichi Kamijo, who have collaborated with him on various projects in the field of peptide research.
Conclusion
Akira Tsugita's innovative methods and contributions to peptide analysis have established him as a key figure in the field. His patents reflect a commitment to advancing scientific understanding and improving analytical techniques.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.