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Title: Aikaterini Kontrogianni-Konstantopoulos: Innovator in Cell Motility Analysis
Introduction
Aikaterini Kontrogianni-Konstantopoulos is a prominent inventor based in Ellicott City, MD, USA. She has made significant contributions in the field of biomedical engineering, particularly with her innovative inventions aimed at advancing cell motility analysis. With four patents to her name, her work is paving the way for enhanced cancer research and treatment methodologies.
Latest Patents
One of her latest patents is titled "Microfluidic chip for analysis of cell motility and methods for using same." This groundbreaking invention describes an integrated apparatus that enables the identification of migratory cells directly from a specimen. The apparatus requires only a small number of cells to perform an assay and includes novel topographic features that can reliably differentiate between migratory and non-migratory cell populations in a sample. It provides the ability to measure both spontaneous and chemotactic migration of cancer cells, helping to distinguish between subpopulations within a tumor sample.
The migratory cells identified using this apparatus can be separated and further analyzed to uncover the factors promoting metastasis. Furthermore, cells in the apparatus can be treated with chemotherapeutic or other agents to determine the most effective drug strategies to inhibit migration. With the use of optically transparent materials, a range of imaging techniques can be utilized for in situ imaging of both migratory and non-migratory cells. Ultimately, this invention is instrumental in predicting the metastatic propensity of tumor cells and selecting optimal drugs for personalized therapies.
Career Highlights
Aikaterini’s professional journey includes notable positions at esteemed institutions such as Johns Hopkins University and the University System of Maryland. Her work in these organizations has significantly contributed to her expertise and the development of her innovative technologies.
Collaborations
Throughout her career, Aikaterini has collaborated with distinguished colleagues, including Konstantinos Konstantopoulos and Colin Dowlin Paul. These partnerships have further enriched her research and innovation efforts, leading to groundbreaking advancements in the analysis of cell motility.
Conclusion
Aikaterini Kontrogianni-Konstantopoulos’s inventive spirit and academic contributions have solidified her status as a leading figure in the field of biomedical engineering. Her work, particularly in the realm of cancer research, is demonstrating profound potential for improving treatment outcomes and personalizing therapies through innovative technology. With her ongoing efforts, she continues to inspire future innovations in scientific research.