The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 06, 2006

Filed:

Sep. 29, 1996
Applicants:

Shoji Kamiya, Kyoto, JP;

Hiroaki Shirahase, Nagaokakyo, JP;

Hiroshi Matsui, Nara, JP;

Shohei Nakamura, Kyoto, JP;

Katsuo Wada, Takatsuki, JP;

Inventors:

Shoji Kamiya, Kyoto, JP;

Hiroaki Shirahase, Nagaokakyo, JP;

Hiroshi Matsui, Nara, JP;

Shohei Nakamura, Kyoto, JP;

Katsuo Wada, Takatsuki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/08 (2005.12); A61K 31/40 (2005.12);
U.S. Cl.
CPC ...
Abstract

A heterocyclic derivative of the formula (I)wherein each symbol is as defined in the specification, and pharmaceutically acceptable salts thereof. The compound (I) of the present invention and pharmaceutically acceptable salts thereof exhibit superior ACAT inhibitory activity and lipoperoxidation inhibitory activity in mammals, and are useful as ACAT inhibitors and lipoperoxidation inhibitors. Specifically, they are useful for the prophylaxis and treatment of arteriosclerosis, hyperlipemia, arteriosclerosis in diabetes, and cerebrovascular and cardiovascular ischemic diseases.


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