The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 15, 2018
Filed:
Jul. 07, 2017
Suzhou Miracpharma Technology Co., Ltd., Suzhou, CN;
Xuenong Xu, Suzhou, CN;
SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD., Suzhou, CN;
Abstract
Disclosed is an intermediate of bemaciclib (also referred to as abemaciclib) having a structure of Formula II, and preparation methods therefor. The preparation methods may comprise condensation, amidine reaction, cyclization and/or other unit reactions. Bemaciclib is obtained through a guanidination reaction and a cyclization reaction using the bemaciclib intermediate disclosed herein as a starting material. starting materials for the preparation methods disclosed herein are easily available, the procedures are simple, and the preparation methods are economical, environmentally friendly and suitable for industrial production.