The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Feb. 22, 2017
Reg Life Sciences, Llc, Ames, IA (US);
Louis Hom, South San Francisco, CA (US);
Na Trinh, Burlingame, CA (US);
Murtaza Alibhai, Austin, TX (US);
Zhihao Hu, South San Francisco, CA (US);
Eli Groban, South San Francisco, CA (US);
Vikranth Arlagadda, South San Francisco, CA (US);
Elizabeth Clarke, South San Francisco, CA (US);
REG Life Sciences, LLC, Ames, IA (US);
Abstract
The present invention relates to novel mutant thioesterase enzymes and naturally-occurring equivalents thereof, compositions made from such enzymes and uses of thioesterase enzymes. In particular, the present invention provides mutant thioesterase enzymes that have altered properties, for example, altered substrate specificity, altered activity, altered selectivity, and/or altered proportional yields in the product mixtures. The present invention also provides polynucleotides encoding such mutant thioesterase enzymes, and vectors and host cells comprising such polynucleotides. The invention further provides for novel uses of thioesterases in the production of various fatty acid derivatives, which are useful as, or as components of, industrial chemicals and fuels.