The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 10, 2018
Filed:
Jun. 09, 2015
Applicants:
Lipomedix Pharmaceuticals Ltd., Jerusalem, IL;
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Inventors:
Assignees:
Lipomedix Pharmaceuticals Ltd., Jerusalem, IL;
The University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 47/48 (2006.01); A61K 31/407 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48046 (2013.01); A61K 9/127 (2013.01); A61K 31/407 (2013.01);
Abstract
A method of treating neoplasia in a subject in need of treatment is provided by administering to the subject an amount of a prodrug of mitomycin C that yields a therapeutically effective amount of mitomycin C, in combination with radiation therapy. In one embodiment, the prodrug of mitomycin C is a liposomal-prodrug of mitomycin C. Together, the prodrug of mitomycin C and radiation therapy provide a synergistic antineoplastic effect.