The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 03, 2018
Filed:
Oct. 14, 2015
Applicant:
Hemarus Therapeutics Limited, Hyderabad, IN;
Inventors:
Ashok Kumar Nuvula, Hyderabad, IN;
Mitali Samaddar, Hyderabad, IN;
Neelima Vadde, Hyderabad, IN;
Zinia Chakraborty, Hyderabad, IN;
Swapna Sagar Duggineni, Hyderabad, IN;
Uma Devi Komath, Hyderabad, IN;
Assignee:
Hemarus Therapeutics Limited, Hyderabad, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/75 (2006.01); A61L 24/10 (2006.01); A61L 24/02 (2006.01); C12N 9/74 (2006.01);
U.S. Cl.
CPC ...
C07K 14/75 (2013.01); A61L 24/02 (2013.01); A61L 24/106 (2013.01); A61L 24/108 (2013.01); C12N 9/6429 (2013.01); C12Y 304/21005 (2013.01);
Abstract
The present invention relates to a chromatographic process for obtaining purified fibrinogen and thrombin from human plasma. The purified fibrinogen and thrombin preparations contain plasminogen in amounts less than 1 ug/mL. The low levels of plasminogen eliminates use of a proteolytic inhibitor, such as aprotinin in fibrin sealant kits which are used for human therapeutic applications.