The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 03, 2018

Filed:

Jun. 27, 2008
Applicants:

George N. Pavlakis, Rockville, MD (US);

John N. Vournakis, Charleston, SC (US);

Barbara K. Felber, Rockville, MD (US);

Sergio Finkielsztein, Newton, MA (US);

Inventors:

George N. Pavlakis, Rockville, MD (US);

John N. Vournakis, Charleston, SC (US);

Barbara K. Felber, Rockville, MD (US);

Sergio Finkielsztein, Newton, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); A61K 38/20 (2006.01); A61K 39/00 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2086 (2013.01); A61K 38/1793 (2013.01); A61K 39/0011 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/55527 (2013.01);
Abstract

The present invention relates to agents that modulate interleukin-15 ('IL-15') signal transduction or function ('Therapeutic Agents') and the use ol″ those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-β-1-♦4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.


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