The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 27, 2018

Filed:

Sep. 10, 2014
Applicant:

Gevo, Inc., Englewood, CO (US);

Inventors:

Reid M. Renny Feldman, San Marino, CA (US);

Uvini Gunawardena, Irvine, CA (US);

Jun Urano, Aurora, CO (US);

Peter Meinhold, Denver, CO (US);

Aristos Aristidou, Highlands Ranch, CO (US);

Catherine Asleson Dundon, Englewood, CO (US);

Christopher Smith, Englewood, CO (US);

Assignee:

Gevo, Inc., Englewood, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/19 (2006.01); C12N 15/81 (2006.01); C12P 7/16 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 9/10 (2006.01); C12N 9/88 (2006.01); C12N 9/90 (2006.01); C12N 9/60 (2006.01);
U.S. Cl.
CPC ...
C12P 7/16 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/1022 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 15/81 (2013.01); C12Y 101/05003 (2013.01); C12Y 202/01006 (2013.01); C12Y 401/01001 (2013.01); C12Y 402/01009 (2013.01); C12Y 101/01001 (2013.01); C12Y 101/01008 (2013.01); C12Y 101/01086 (2013.01); C12Y 401/01074 (2013.01); Y02E 50/10 (2013.01);
Abstract

The present invention provides recombinant microorganisms comprising an isobutanol producing metabolic pathway and methods of using said recombinant microorganisms to produce isobutanol. In various aspects of the invention, the recombinant microorganisms may comprise a modification resulting in the reduction of pyruvate decarboxylase and/or glycerol-3-phosphate dehydrogenase activity. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.


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