The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2018
Filed:
Sep. 05, 2014
Applicant:
Glycom A/s, Hørsholm, DK;
Inventors:
Gyula Dekany, Sinnamon Park, AU;
Pauline Peltier-Pain, Orleans, FR;
Dóra Molnár-Gábor, Budapest, HU;
Markus Hederos, Svedala, SE;
Assignee:
GLYCOM A/S, Hørsholm, DK;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 19/18 (2006.01); C07H 3/02 (2006.01); C07H 3/06 (2006.01); C12P 19/04 (2006.01); C12P 19/00 (2006.01); C07H 1/00 (2006.01);
U.S. Cl.
CPC ...
C12P 19/18 (2013.01); C07H 1/00 (2013.01); C07H 3/02 (2013.01); C07H 3/06 (2013.01); C12P 19/00 (2013.01); C12P 19/04 (2013.01); C12Y 302/01051 (2013.01);
Abstract
The present application discloses a method of making a mixture of 2'-FL and DFL in high yield by culturing, with lactose, a genetically modified cell having a recombinant gene that encodes a single fucosyl transferase. The resulting mixture of 2′-FL and DFL can be subjected to hydrolysis initiated by an acid or mediated by a fucosidase to produce fucose in high yields.