The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 20, 2018
Filed:
May. 16, 2013
Cofco Biochemical (Anhui) Co., Ltd, Bengbu, Anhui, CN;
Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, CN;
Guojun Yue, Anhui, CN;
Jibin Sun, Tianjin, CN;
Ping Zheng, Tianjin, CN;
Jiao Liu, Tianjin, CN;
Qinggang Li, Tianjin, CN;
Linghe Xia, Anhui, CN;
Yongsheng Zhou, Anhui, CN;
Hu Luo, Anhui, CN;
Yong Zhou, Anhui, CN;
Yun Man, Anhui, CN;
Zongmei Lu, Anhui, CN;
Yanhe Ma, Tianjin, CN;
Abstract
Provided in the present invention is an asparaginic acid kinase, and the 340amino acid residue in the position of the amino acid sequence of the asparaginic acid kinase corresponding to the amino acid sequence shown in SEQ ID NO: 2 is a non-aspartic acid. The asparaginic acid of the present invention can efficiently relieve the feedback inhibition of L-lysine, and can be effectively used for the production of L-lysine. Also provided in the present invention are host cells comprising genes coding the asparaginic acid kinase and a method for producing L-lysine using the host cells or the asparaginic acid kinase. The asparaginic acid kinase of the present invention or the host cells comprising the asparaginic acid kinase of the present invention is also used to produce L-threonine, L-methionine, L-isoleucine or L-valine. Also provided in the present invention is a method of producing L-aspartyl-4-yl phosphoric acid using the asparaginic acid kinase or the host cells.